As a consequence, any daughter B cells will acquire slight amino acid differences in the variable domains of their antibody chains.
4.
An alternative approach is to split the dimeric variable domains from common immunoglobulin G ( IgG ) from humans or mice into monomers.
5.
Specialized constraint propagation techniques for cumulative constraints exists; different techniques are used depending on which variable domains are already reduced to a single value.
6.
Another amide ring occurs at the interior of the variable domains of some Immunoglobulin G antibodies and assists in linking the two beta-sheets.
7.
Syndecan-4 also binds to phosphatidylinositol ( 4, 5 )-bisphosphate ( PIP2 ) through the variable domain and increases PKC activity ten-fold.
8.
There are two types of light chains : kappa and lambda, each composed of a constant domain ( CL ) and a variable domain ( VL ).
9.
The variable domain exon is rejoined through a process called non-homologous end joining ( NHEJ ) to the desired constant region ( ?, ? or ? ).
10.
Another possibility is that the toxins produced by this bacteria could act as superantigens that activate directly the T-cells over the variable domain of t-cell receptors.